المجلة الأكاديمية للإعجاز العلمي في القرآن والسنة (ISSN 2356-9824)
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إصدارات المجلة

العلوم الأساسية (فيزياء–كيمياء-رياضيات)

العلوم الفلكية ,الجوية والأرضية❱ ❰العلوم الأساسية والهندسة❱ ❰ الطب والصيدلة والأحياء❱ ❰العلوم الأساسية (فيزياء–كيمياء-رياضيات)❱ ❰الإعجاز اللغوي والبياني والبلاغي❱ ❰الإعجاز التشريعي❱ ❰الإعجاز التأريخي

 

Fruits of Haven and Their Role in Cancer Prevention

2016-09-17 & doi: 10.19138/miracles.37.5
العلوم الأساسية (فيزياء–كيمياء-رياضيات)

Apart from spiritual, behavioral and social guidance to the world, the Holy Qur’an has also prescribed a number of medicines and therapeutic methodologies to treat and prevent numerous human ailments. In addi-tion to the nutrition, food and dietary supplements the Holy Qur’an has directly emphasized several fruits for their health benefits and curative effects. Among the medicinal fruits, banana, grape, date, fig, olive and pomegranate are prominently discussed in the Holy Qur’an. Thus, in the present study an attempt is made to explore the therapeutic potentials of the fruits. Different parts of the mentioned fruits were subjected to se-quential extraction method started with n-hexane then followed by ethanol and water. Cytotoxicity of the ex-tracts was determined by dimethylthiazol-2-yl - 2,5 diphenyl tetrazolium bromide (MTT) assay on 2 human cancer (colon and breast) and normal endothelial cell. The antioxidant potencies were assessed using DPPH (1,1-diphenyl-2-picrylhydrazyl) and FRAP (Ferric reducing antioxidant power) assays. The results indicated that all the fruits tested in the study exhibited remarkable in vitro anticancer activity by against human breast (MCF-7) and colon (HCT 116) cancer cells. The IC50 values were ranged between 11.42 and 58.60 µg/ml. The significant antiproliferative effect of the fruits could probably due to the strong antioxidant effect, as all the tested fruits, except banana, displayed lowest IC50 values in DPPH and FRAP free radicals. The fruits ex-tracts displayed IC50 values range between 6.06 and 70.50 µg/ml against DPPH, whereas, 10.20 to 95.20 µg/ml against FRAP. These results are in good agreement with the medicinal uses of the fruits suggested in the Holy Qur’an to cure the human ailments.

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